Evidence map›Paper›PMID 42794816›Full record

ArticleInternational journal of molecular sciences2026

Botanical Substitution in Traditional 'Rang Chuet' Preparations: Distinguishing the Potential Xenobiotic Modulation of

Kitti Leesiam, Arunporn Itharat, Weerachai Pipatrattanaseree, Puritat Kanokkangsadal, Thishnapha Vudhironarit, Vilailak Tiyao, Sunita Makchuchit, Pranporn Kuropakornpong, Neal M Davies

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kitti LeesiamGraduate School, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani 12120, Thailand.
Arunporn ItharatDepartment of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani 12120, Thailand.
Weerachai PipatrattanasereeRegional Medical Science Center 12 Songkhla, Ministry of Public Health, Mueang Songkhla, Songkhla 90100, Thailand.
Puritat KanokkangsadalDepartment of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Klongluang, Pathumthani 12120, Thailand.ORCID 0000-0002-9203-3074
Thishnapha VudhironaritDepartment of Pharmacology, Phramongkutklao College of Medicine, Ratchathewi, Bangkok 10400, Thailand.
Vilailak TiyaoCenter of Excellence in Applied Thai Traditional Medicine Research (CEATMR), Thammasat University, Klongluang, Pathumthani 12120, Thailand.
Sunita MakchuchitCenter of Excellence in Applied Thai Traditional Medicine Research (CEATMR), Thammasat University, Klongluang, Pathumthani 12120, Thailand.ORCID 0000-0002-9863-0734
Pranporn KuropakornpongCenter of Excellence in Applied Thai Traditional Medicine Research (CEATMR), Thammasat University, Klongluang, Pathumthani 12120, Thailand.
Neal M DaviesFaculty of Pharmacy and Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AB T6G 2E1, Canada.ORCID 0000-0002-7050-1471

Funding

the Thailand Science Research and Innovation Fundamental Fund fiscal year 2023 (Grant No. TUFF 60/2566 the Thailand Science Research and Innovation Fundamental Fund fiscal year 2023 (Grant No. TUFF 60/2566
6 · The paper itself

Abstract

Rang Chuet is a traditional Thai medicinal plant widely used for detoxification, although the name is applied to several botanically distinct species. This study investigated the ethnopharmacological basis and potential molecular mechanisms underlying this practice by integrating practitioner knowledge, botanical authentication, phytochemical profiling, and molecular docking. Structured interviews were conducted with 30 experienced traditional medicine practitioners from five regions of Thailand to document the therapeutic use and preparation of Rang Chuet. Botanical identification confirmed three species marketed under this name:

Indexed as

CrotalariaEuphorbiaceaePlant ExtractsXenobioticsHumansMedicine, Thai TraditionalMolecular Docking SimulationPhytochemicalsPlants, MedicinalPhytochemicalsPlant ExtractsXenobioticsdetoxificationethnopharmacologymolecular dockingRang Chuet

Identifiers

PMID42794816
PMCPMC13607412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.