ArticleInternational journal of molecular sciences2026
A Regulatory Network of Transcription and Hormones Controls PCD and Autophagy in Grape Seed Abortion.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The seedless trait in grapes primarily arises from pseudo-parthenocarpy, driven by early seed abortion involving programmed cell death (PCD) and autophagy. However, the specific regulatory networks governing these pathways remain poorly defined. To address this, we systematically characterized the PCD-related (vacuolar processing enzyme [VPE] and metacaspase [MC]) and autophagy-related (ATG) gene families in the seedless cultivar 'Jingkejing' utilizing comprehensive bioinformatic analyses, spatiotemporal transcriptomic profiling, and transient expression assays. We identified three VPE, six MC, and 33 ATG genes, whose promoters were significantly enriched in hormone-responsive and transcription factor (TF)-binding motifs. Transcriptomic profiling across critical seed abortion stages highlighted
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