Evidence map›Paper›PMID 42794770›Full record

ArticleInternational journal of molecular sciences2026

Naturally Occurring Variability in the Regulatory Region of the

Alexander V Symonenko, Natalia V Roshina, Olga Y Rybina, Evgeniya A Tsybul'ko, Anna V Krementsova, Elena A Mikhaleva, Vladimir E Alatortsev, Dmitry V Mukha, Elena G Pasyukova

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In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander V SymonenkoNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.ORCID 0000-0003-1473-4470
Natalia V RoshinaNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.
Olga Y RybinaNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.
Evgeniya A Tsybul'koNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.
Anna V KrementsovaNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.ORCID 0000-0003-0416-7222
Elena A MikhalevaNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.ORCID 0000-0002-2665-7137
Vladimir E AlatortsevNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.
Dmitry V MukhaVavilov Institute of General Genetics, Russian Academy of Sciences, 3 Gubkin Str., 119991 Moscow, Russia.ORCID 0000-0002-7380-0776
Elena G PasyukovaNational Research Centre "Kurchatov Institute", 2 Kurchatov Sq., 123182 Moscow, Russia.

Funding

National Research Centre "Kurchatov Institute"
6 · The paper itself

Abstract

Revealing gene expression patterns is essential for comprehending the genetic control of complex traits like lifespan. Analyzing structural variation in gene regulatory regions within natural populations is a promising approach in functional genetics, allowing us to identify regulatory sites that influence transcription and phenotype in vivo. We describe the structural variability of the 5' regulatory region of the

Indexed as

Drosophila melanogasterDrosophila ProteinsGene Expression RegulationLongevityRegulatory Sequences, Nucleic AcidTranscription FactorsAllelesAnimalsPolymorphism, Single NucleotideDrosophila ProteinsTranscription Factorscold toleranceDrosophila melanogasterlifespannatural populationspolymorphismSNPtranscriptiontranscription factors

Identifiers

PMID42794770
PMCPMC13607089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.