Evidence map›Paper›PMID 42794742›Full record

ArticleInternational journal of molecular sciences2026

Alexander D Law, Mikah Brandes, Melissa Bollen, Amala Soumyanath, Doris Kretzschmar

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander D LawBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0002-0954-7147
Mikah BrandesBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-0892-1608
Melissa BollenBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Amala SoumyanathBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-1569-6453
Doris KretzschmarBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.

Funding

Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2020 to 2024
$6.1M
NCCIH NIH HHS U19 AT010829NIH HHS 5U19AT010829-24
6 · The paper itself

Abstract

With increasing global life expectancy, there is a growing need for strategies to mitigate age-related declines in fitness and health.

Indexed as

AgingDrosophila melanogasterDrosophila ProteinsPlant ExtractsProto-Oncogene Proteins c-aktWithaniaAnimalsLongevityPhosphorylationSignal TransductionTOR Serine-Threonine KinasesAshwagandhaDrosophila ProteinsPlant ExtractsProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesagingAktashwagandhaDrosophila melanogasterFOXOinsulin signalingKeaplocomotionlongevityNRF2

Identifiers

PMID42794742
PMCPMC13607971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.