Evidence map›Paper›PMID 42794628›Full record

ArticleInternational journal of molecular sciences2026

Androgen Receptor T878A and L702H Alterations Define Subsets of Prostate Cancer Patients with Distinct Outcomes to Androgen Receptor Pathway Inhibitors.

Matthew Siskin, Jayati Saha, Emmanuel S Antonarakis, Alessandro Leal, Samuel Parry, David R Wise

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew SiskinPerlmutter Cancer Center, NYU Langone Health, 160 E 34th Street, New York, NY 10016, USA.ORCID 0000-0001-5948-997X
Jayati SahaGuardant Health, 3100 Hanover St., Palo Alto, CA 94304, USA.
Emmanuel S AntonarakisMasonic Cancer Center, University of Minnesota, 909 Fulton Street SE, Minneapolis, MN 55455, USA.
Alessandro LealPerlmutter Cancer Center, NYU Langone Health, 160 E 34th Street, New York, NY 10016, USA.ORCID 0000-0001-7967-3213
Samuel ParryPerlmutter Cancer Center, NYU Langone Health, 160 E 34th Street, New York, NY 10016, USA.ORCID 0000-0002-0456-700X
David R WisePerlmutter Cancer Center, NYU Langone Health, 160 E 34th Street, New York, NY 10016, USA.ORCID 0000-0003-3419-4723

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
NCI NIH HHS P30 CA077598
6 · The paper itself

Abstract

Metastatic androgen pathway modulation-resistant (mAPMR) prostate cancer subtypes harboring

Indexed as

Androgen Receptor AntagonistsProstatic NeoplasmsReceptors, AndrogenAgedBenzamidesDrug Resistance, NeoplasmHumansMaleMutationNitrilesPhenylthiohydantoinSignal TransductionTreatment OutcomeAndrogen Receptor AntagonistsAR protein, humanBenzamidesenzalutamideNitrilesPhenylthiohydantoinReceptors, Androgenandrogen receptorARPIcfDNAmAPMRmCRPCprecision medicineprostate cancer

Identifiers

PMID42794628
PMCPMC13607047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.