Evidence map›Paper›PMID 42794621›Full record

ArticleInternational journal of molecular sciences2026

Bioactivity-Guided Optimization of 3-Deoxyanthocyanidin Extraction and Seasonal Mapping of Four Morphotypes of

Paulo Victor R Souza, Ygor Jessé Ramos, João Victor Silva-Silva, Maria do Socorro S Chagas, Adélia Viviane de Luna, Katia S Calabrese, Fernando Almeida-Souza, Davyson L Moreira, Carla J Moragas-Tellis, Maria D Behrens

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paulo Victor R SouzaLaboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0003-4732-3571
Ygor Jessé RamosFarmácia da Terra Laboratory, School of Pharmacy, Federal University of Bahia, Salvador 40170-115, BA, Brazil.ORCID 0000-0003-4443-1008
João Victor Silva-SilvaInstitute of Mathematics and Computer Sciences, University of São Paulo, São Carlos 13566-590, SP, Brazil.ORCID 0000-0002-7064-2610
Maria do Socorro S ChagasLaboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-3335-6981
Adélia Viviane de LunaLaboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0009-0002-3609-753X
Katia S CalabreseLaboratory of Protozoology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-1884-3765
Fernando Almeida-SouzaLaboratory of Protozoology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0003-0047-6159
Davyson L MoreiraNatural Products and Biochemistry Laboratory, Rio de Janeiro Botanical Garden Research Institute, Rio de Janeiro 22460-030, RJ, Brazil.ORCID 0000-0002-3060-0395
Carla J Moragas-TellisLaboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0001-9834-2874
Maria D BehrensLaboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-1097-2909

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 150588/2026-7Conselho Nacional de Desenvolvimento Científico e Tecnológico 309493/2025-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 309527/2025-2Conselho Nacional de Desenvolvimento Científico e Tecnológico 442053/2024-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 447627/2024-4
6 · The paper itself

Abstract

Ultrasound-assisted extraction (UAE) was combined with a design of experiments (DoE) to optimize the recovery of 3-deoxyanthocyanidins (3D-anths) from

Indexed as

AnthocyaninsAntiprotozoal AgentsPlant ExtractsChromatography, High Pressure LiquidLeishmaniaPlant LeavesSeasonsAnthocyaninsAntiprotozoal AgentsPlant Extracts3-deoxyanthocyanidinscarajurinDoEFridericia chicaHPLC analysisLeishmania amazonensisUAE

Identifiers

PMID42794621
PMCPMC13607019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.