ReviewInternational journal of molecular sciences2026
Macrophage-Fibroblast Crosstalk in Kidney Injury: A Narrative Review.
Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Renal fibrosis is a multifaceted pathological process driven by cellular interactions, with fibroblasts and macrophages serving as central regulators. Fibroblasts activate into matrix-producing myofibroblasts, directly contributing to fibrogenesis and disease progression. Macrophages, characterized by pronounced heterogeneity, dynamically modulate the balance between tissue injury and repair, thereby critically influencing disease outcomes. The crosstalk between these two cell types operates through diverse signaling pathways, extracellular vesicle-mediated communication, and metabolic reprogramming, forming an intricate regulatory network that exerts stage-specific effects during renal injury. Recent insights into fibroblast activation, macrophage polarization, and their intercellular interplay have provided potential therapeutic avenues for delaying kidney fibrosis, offering renewed promise for clinical translation.
Indexed as
Identifiers
42794608What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.