Evidence map›Paper›PMID 42794519›Full record

ArticleInternational journal of molecular sciences2026

Expression and Immunogenic Application of Recombinant DENV-2 rprM Protein for the Non-Invasive Detection of Salivary IgA Antibodies.

Julio García-Cordero, Luis Alberto Sánchez-Vargas, Rosendo Luria-Pérez, Héctor Vivanco-Cid, Leticia Cedillo-Barrón, Jazmín García-Machorro, Gabriela Mellado-Sánchez

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julio García-CorderoDepartamento de Biomedicina Molecular, Centro de Investigación y Estudios Avanzados (CINVESTAV-IPN), Mexico City 07360, Mexico.ORCID 0000-0003-3369-8591
Luis Alberto Sánchez-VargasCentro de Investigaciones Científicas, Instituto de Biotecnología, Universidad del Papaloapan, Oaxaca 68301, Mexico.ORCID 0000-0003-4622-5427
Rosendo Luria-PérezUnidad de Investigación en Enfermedades Oncológicas, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.ORCID 0000-0002-5822-6956
Héctor Vivanco-CidInstituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz 91700, Mexico.
Leticia Cedillo-BarrónDepartamento de Biomedicina Molecular, Centro de Investigación y Estudios Avanzados (CINVESTAV-IPN), Mexico City 07360, Mexico.ORCID 0000-0003-2642-3872
Jazmín García-MachorroLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-3630-5979
Gabriela Mellado-SánchezUnidad de Desarrollo e Investigación en Bioterapéuticos (UDIBI), Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-8299-5958

Funding

CONACyT CB-2014-01#238736CONACyT SIP 20260338Hospital Infantil de México Federico Gómez HIM-2018-080-SSA 1543Programa para el Desarrollo Profesional Docente 103.5/13/7135
6 · The paper itself

Abstract

Dengue virus (DENV) serotypes 1-4 cause dengue, a major re-emerging disease in tropical and subtropical regions. This study evaluated the antigenicity of a recombinant DENV-2 premembrane protein (rprM-DENV-2) and its ability to detect anti-DENV human IgA antibodies. The rprM-DENV-2 protein was expressed in

Indexed as

Antibodies, ViralDengueDengue VirusImmunoglobulin ASalivaAnimalsChlorocebus aethiopsEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin GRatsRecombinant ProteinsVero CellsAntibodies, ViralImmunoglobulin AImmunoglobulin GRecombinant Proteinsantibody responseantigenicityantiviral immunitydengueinnovationnon-invasive approachprM proteinproof-of-principlesalivary IgAviral infection

Identifiers

PMID42794519
PMCPMC13606918

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.