Evidence map›Paper›PMID 42794500›Full record

ArticleInternational journal of molecular sciences2026

Calcium-Triggered PuMYB44-PuERF118 Cascade Activates

Xinyu Wang, Gaifang Yao, Min Zhang, Huihui Song, Zhen Cao, Kangdi Hu, Xinxin Gai, Hua Zhang, Gaihua Qin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinyu WangKey Laboratory of Germplasm Innovation and Utilization of Horticultural Crop (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Institute of Horticultural Research, Anhui Academy of Agricultural Sciences, Hefei 230031, China.
Gaifang YaoSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Min ZhangSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Huihui SongSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Zhen CaoKey Laboratory of Germplasm Innovation and Utilization of Horticultural Crop (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Institute of Horticultural Research, Anhui Academy of Agricultural Sciences, Hefei 230031, China.
Kangdi HuSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID 0000-0002-1195-389X
Xinxin GaiSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Hua ZhangSchool of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.ORCID 0000-0003-3980-1262
Gaihua QinKey Laboratory of Germplasm Innovation and Utilization of Horticultural Crop (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Institute of Horticultural Research, Anhui Academy of Agricultural Sciences, Hefei 230031, China.ORCID 0000-0003-3226-437X

Funding

Anhui Academy of Agricultural Sciences No. AHYY2023004National Natural Science Foundation of China 32272682National Natural Science Foundation of China 32472708
6 · The paper itself

Abstract

Fruit aroma is a key factor shaping the commercial value of pears. MYB and ERF transcription factors (TFs) are involved in regulating the biosynthesis of fruit aroma compounds, yet the mechanisms underlying their synergistic regulation of pear aroma formation remain elusive. Calcium signaling exerts an important role in fruit aroma biosynthesis; nevertheless, how calcium signaling mediates MYB-ERF transcription factors to participate in pear aroma biosynthesis remains unclear. Here, transcriptomic profiling of calcium-treated pear fruits screened two significantly upregulated TFs, PuMYB44 and PuERF118, as candidate genes. Phylogenetic analysis and conserved domain characterization further suggested that these two genes may be involved in regulating fatty acid biosynthesis. Transient overexpression experiments in pear fruits revealed that the co-expression of PuMYB44 and PuERF118 synergistically activated a set of fatty acid biosynthesis genes, including

Indexed as

CalciumFruitOdorantsPlant ProteinsPyrusTranscription FactorsGene Expression Regulation, PlantPhylogenyPromoter Regions, GeneticCalciumPlant ProteinsTranscription Factorsaromapear (Pyrus ussuriensis)PuFAD8PuMYB44-PuERF118transcriptional regulation

Identifiers

PMID42794500
PMCPMC13607563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.