Evidence map›Paper›PMID 42794482›Full record

ReviewInternational journal of molecular sciences2026

Mapping the MicroRNA Landscape of Cadmium Exposure: A Bibliometric and Bioinformatics Analysis of Molecular Targets and Regulatory Pathways.

Muhammet Kesin, Gözde Oztan, Halim Işsever

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Muhammet KesinSafranbolu State Hospital, Safranbolu, Karabük 78600, Türkiye.ORCID 0000-0002-4381-2557
Gözde OztanDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Türkiye.ORCID 0000-0002-2970-1834
Halim IşseverDepartment of Public Health, Istanbul Faculty of Medicine, Istanbul University, Istanbul 34093, Türkiye.ORCID 0000-0002-5435-706X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium is a persistent toxic metal that promotes oxidative stress, inflammation, and epigenetic dysregulation; however, the research landscape and recurrent microRNA (miRNA)-mediated responses associated with cadmium exposure remain incompletely characterized. This study integrated bibliometric, structured content, and bioinformatics analyses to identify major research trends and recurrent miRNA signals. PubMed/MEDLINE, Scopus, and Web of Science Core Collection were searched using predefined cadmium- and miRNA-related search terms, yielding 1511 source records. After language/document-type filtering and cross-database deduplication, 817 unique records remained for screening, of which 286 publications formed the final bibliometric corpus. Author-keyword co-occurrence analysis was performed using a minimum occurrence threshold of ≥3, with ≥5 used as a sensitivity analysis. Cadmium and microRNA remained the dominant thematic core, while heavy-metal toxicity, apoptosis, and cadmium-stress responses represented the most recurrent secondary themes. In the final human-relevant biological evidence corpus (

Indexed as

CadmiumComputational BiologyEnvironmental ExposureMicroRNAsAnimalsBibliometricsGene Expression RegulationGene Regulatory NetworksHumansOxidative StressCadmiumMicroRNAsapoptosisbibliometric analysisbioinformaticscadmium exposureepigeneticsinflammationmicroRNAoxidative stress

Identifiers

PMID42794482
PMCPMC13607735

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.