ArticleInternational journal of molecular sciences2026
Altered Maternal Circulating and Placental microRNA-369-5p and microRNA-671-3p Expression in Intrahepatic Cholestasis of Pregnancy: Comparison of ICSI and Spontaneous Conception.
Sibel Bulgurcuoglu Kuran, Meryem Hocaoglu, Selin Demirer, Esra Kaynak, Ilayda Loçlar Karaalp, Elvan Yagimli Ozturk, Ayse Altun, Ibrahim Sogut, Canan Hurdag, Abdulkadir Turgut and 1 more
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In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Sibel Bulgurcuoglu KuranDepartment of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, IVF Unit, Istanbul Medical Faculty, Istanbul University, 34093 Istanbul, Turkey.ORCID 0000-0003-4267-2158 Meryem HocaogluDepartment of Obstetrics and Gynecology, Goztepe Prof Dr. Suleyman Yalcin City Hospital Affiliated to Istanbul Medeniyet University, 34722 Istanbul, Turkey.
Selin DemirerDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, 34093 Istanbul, Turkey.
Esra KaynakDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, 34093 Istanbul, Turkey.ORCID 0000-0003-2651-0538 Ilayda Loçlar KaraalpDepartment of Obstetrics and Gynecology, Goztepe Prof Dr. Suleyman Yalcin City Hospital Affiliated to Istanbul Medeniyet University, 34722 Istanbul, Turkey.ORCID 0000-0002-6968-4450 Elvan Yagimli OzturkDepartment of Obstetrics and Gynecology, Goztepe Prof Dr. Suleyman Yalcin City Hospital Affiliated to Istanbul Medeniyet University, 34722 Istanbul, Turkey.
Ayse AltunDepartment of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, IVF Unit, Istanbul Medical Faculty, Istanbul University, 34093 Istanbul, Turkey.
Ibrahim SogutDepartment of Biochemistry, Faculty of Medicine, Demiroglu Bilim University, 34394 Istanbul, Turkey.ORCID 0000-0001-7724-6488 Canan HurdagDepartment of Histology and Embryology, Faculty of Medicine, Demiroglu Bilim University, 34394 Istanbul, Turkey.
Abdulkadir TurgutDepartment of Obstetrics and Gynecology, Goztepe Prof Dr. Suleyman Yalcin City Hospital Affiliated to Istanbul Medeniyet University, 34722 Istanbul, Turkey.ORCID 0000-0002-3156-2116 Evrim Komurcu BayrakDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, 34093 Istanbul, Turkey.ORCID 0000-0003-1271-1208 Funding
Istanbul University The present research was supported by the Scientific Research Projects Coordination Unit of Istanbul University (Project numbers: TSA-2019-33570)
6 · The paper itselfAbstract
To investigate microRNA-369-5p (miR-369-5p) and miR-671-3p expression in maternal peripheral blood leukocytes, plasma, and placental tissue in women with intrahepatic cholestasis of pregnancy (ICP) undergoing intracytoplasmic sperm injection (ICSI), compared with spontaneous conception. In this exploratory cohort study, microRNA-369-5p (miR-369-5p) and microRNA-671-3p (miR-671-3p) expression levels were analyzed using real-time quantitative PCR in maternal peripheral blood leukocytes, plasma, and placental tissue in four groups: (1) women with uncomplicated pregnancies conceived via intracytoplasmic sperm injection (non-ICP-ICSI,
Indexed as
Cholestasis, IntrahepaticMicroRNAsPlacentaPregnancy ComplicationsSperm Injections, IntracytoplasmicAdultFemaleGene Expression RegulationHumansLeukocytesPregnancyMicroRNAsintracytoplasmic sperm injectionintrahepatic cholestasis of pregnancyleukocytesmicroRNA-369-5pmicroRNA-671-3pplacentaplasma
Identifiers
PMID42794448
PMCPMC13606310
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