Evidence map›Paper›PMID 42794438›Full record

ArticleInternational journal of molecular sciences2026

Clonal Dynamics After Allogeneic Hematopoietic Stem Cell Transplantation from Related Donors: A Case Series.

Valentina Giudice, Denise Morini, Maddalena Langella, Francesco Verdesca, Francesca Velino, Anna Maria Sessa, Simona Caruso, Martina De Leucio, Pasqualina Scala, Italia Conversano and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Valentina GiudiceHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.ORCID 0000-0002-7492-6848
Denise MoriniHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Maddalena LangellaHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Francesco VerdescaHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Francesca VelinoHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Anna Maria SessaHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Simona CarusoHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.ORCID 0000-0001-7267-8310
Martina De LeucioHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Pasqualina ScalaHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Italia ConversanoHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Anna Maria Della CorteHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Danilo De NovellisHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.ORCID 0000-0002-2590-0529
Bianca SerioHematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.

Funding

European Union PNRR-POC-2023-12377396University of Salerno 300397FRB24GIUDIUniversity of Salerno 300397FRB25GIUDI
6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (HSCT) serves as a critical model for investigating clonal dynamics, as hematopoietic reconstitution occurs amidst significant proliferative stress and immune-mediated pressures. This study utilized longitudinal next-generation sequencing of a 30-gene panel to track clonal evolution in 20 patients and their matched-related or haploidentical donors. The findings revealed that post-transplant hematopoiesis is frequently driven by donor-derived clones, with

Indexed as

Clonal EvolutionClonal HematopoiesisHematopoietic Stem Cell TransplantationTissue DonorsAdultDioxygenasesDNA-Binding ProteinsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3AFemaleHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedMutationProto-Oncogene ProteinsDioxygenasesDNA-Binding ProteinsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNMT3A protein, humanProto-Oncogene ProteinsTET2 protein, humanclonal dynamicsclonal hematopoiesishematopoietic stem cell transplantationmatched-related donor

Identifiers

PMID42794438
PMCPMC13606576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.