ArticleChildren (Basel, Switzerland)2026
Short-Term Associations Between Relative Humidity and Pediatric Afebrile Seizure Presentations: A Distributed Lag Non-Linear Time-Series Study.
Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association between daily meteorological variability and pediatric afebrile seizure presentations using ecological time-series analysis and Distributed Lag Non-linear Models (DLNMs).
methodsThis retrospective ecological time-series study was conducted in a tertiary pediatric emergency department in northwestern Türkiye. Pediatric seizure-related presentations recorded between January 2019 and December 2023 were retrospectively screened for case identification and clinical validation. The primary environmental exposure analysis was restricted to eligible afebrile seizure presentations occurring during the 2023 calendar year and linked to synchronized daily meteorological data. Associations between meteorological variables and daily afebrile seizure presentation counts were assessed using multivariable Quasi-Poisson regression and Distributed Lag Non-linear Models (DLNMs).
resultsAmong 777 screened seizure-related presentations, 67 children contributing 157 afebrile seizure presentations during 2023 were included. Relative humidity showed the strongest independent association with pediatric afebrile seizure presentations. Each 10-percentage-point increase in relative humidity was associated with an 18.6% higher rate of pediatric afebrile seizure presentations (IRR = 1.186; 95% CI: 1.103-1.275;
conclusionsHigher relative humidity was associated with increased pediatric afebrile seizure presentations and represented the only meteorological exposure demonstrating both significant contemporaneous and cumulative delayed associations. These findings suggest that meteorological variability, particularly relative humidity, may contribute to short-term and delayed fluctuations in seizure-related healthcare utilization among children. Given the single-center ecological design and the one-year environmental exposure period, these findings should be interpreted as population-level and hypothesis-generating and should not be considered a basis for individual risk prediction or humidity-based clinical counseling. Further multicenter, multi-year prospective studies incorporating individual-level and higher-resolution environmental exposure assessment are needed to confirm these findings and clarify the biological mechanisms underlying humidity-associated seizure susceptibility in pediatric populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.