Evidence map›Paper›PMID 42794254›Full record

ArticleChildren (Basel, Switzerland)2026

Combining Neuromuscular Electrical Stimulation with Activity Based Training in Children with Chronic Cervical Spinal Cord Injury: A Retrospective Case Series.

Kathryn Noonan-Eaton, Beatrice Ugiliweneza, Andrea L Behrman, Goutam Singh

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Kathryn Noonan-EatonPediatric NeuroRecovery Translational Program, Louisville, KY 40202, USA.
Beatrice UgiliwenezaKentucky Spinal Cord Injury Research Center, Louisville, KY 40202, USA.ORCID 0000-0001-7334-6924
Andrea L BehrmanPediatric NeuroRecovery Translational Program, Louisville, KY 40202, USA.ORCID 0000-0003-1859-8787
Goutam SinghKentucky Spinal Cord Injury Research Center, Louisville, KY 40202, USA.ORCID 0000-0002-3382-2321

Funding

Kosair for Kids GB141540
6 · The paper itself

Abstract

BACKGROUND/

objectivesNeuromuscular electrical stimulation (NMES) is a promising adjunct to activity-based training for individuals with spinal cord injury (SCI). While lower extremity NMES applications are well documented, upper extremity (UE) outcomes remain underexplored in pediatric SCI. The objective of this case series was to evaluate outcomes following a combined NMES and activity-based therapy program targeting the UE in children with chronic SCI.

methodsIn this retrospective case series, we analyzed outcomes from five children, ages 4 to 15 years old, with chronic cervical level SCI who completed an individualized activity-based training program with concurrent wide pulse neuromuscular electrical stimulation (WPS-NMES). Participants were children with chronic SCI (≥6 months post-injury). Functional assessments were conducted by pre- and post-intervention. Pre- and post-intervention outcomes were summarized descriptively at the individual case level.

resultsFive children with chronic cervical SCI (ages 4-15 years) completed a mean of 54 intervention sessions. All patients demonstrated improved trunk control, with Segmental Assessment of Trunk Control (SATCo) increases of 1-6 points. UE gains on the Peds-NRS were observed in 4/5 patients, primarily in overhead reach and object-to-mouth items. Box and Blocks Test scores improved in 4/5 patients in at least one UE, while one patient remained at 0 bilaterally, and one patient experienced a unilateral decline. One patient demonstrated proximal and trunk improvements without changes in manual dexterity. No unanticipated adverse events were reported.

conclusionsObserved improvements in selected trunk and UE outcomes occurred during participation in a multimodal rehabilitation program incorporating WPS-NMES. These preliminary findings describe functional changes observed during the rehabilitation program and may help inform the design of future controlled studies evaluating multimodal rehabilitation approaches for children with chronic SCI.

Indexed as

activity-based trainingneuromuscular electrical stimulationspinal cord injuryupper extremity function

Identifiers

PMID42794254
PMCPMC13605759

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