Evidence map›Paper›PMID 42793466›Full record

ArticleHealthcare (Basel, Switzerland)2026

Physicians' Perspectives on Access to Innovative Oncology Therapies: A Cross-Sectional Survey in Bulgaria.

Iva Zdravkova-Aneva, Tihomir Dermendzhiev, Kostadin Kostadinov, Angel Prodanov, Rositsa Dimova, Ralitsa Raycheva

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iva Zdravkova-AnevaDepartment of Social Medicine and Public Health, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Tihomir DermendzhievDepartment of Medical microbiology and immunology "Prof. Dr. Elissay Yanev", Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Kostadin KostadinovDepartment of Social Medicine and Public Health, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-1414-8738
Angel ProdanovDepartment of Anaesthesiology and Intensive Care Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Rositsa DimovaDepartment of Health Management and Health Economics, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Ralitsa RaychevaDepartment of Social Medicine and Public Health, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0002-6417-5681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDespite major advances in precision medicine, equitable and timely access to innovative oncology therapies remains challenging because of differences in reimbursement systems, health technology assessment (HTA), and healthcare organization. Physicians are well positioned to identify barriers affecting the implementation of these therapies in routine practice. This study evaluated Bulgarian physicians' perceptions of innovative oncology therapies, assessed patient access, identified barriers to timely availability, and examined factors perceived as associated with these perceptions.

methodsA cross-sectional web-based survey was conducted between March and May 2025 among physicians involved in oncology care in Bulgaria. The questionnaire comprised six domains addressing professional characteristics, self-perceived knowledge, clinical implementation, perceptions of patient access, barriers to implementation, and policy priorities. Descriptive statistics, Pearson's chi-square tests, Cramér's V, and multivariable ordinal logistic regression were used to analyze the data.

resultsA total of 114 physicians participated. Respondents generally reported moderate-to-high levels of self-perceived knowledge regarding innovative oncology therapies. Self-perceived knowledge was higher among medical oncologists (adjusted

conclusionsBulgarian oncology specialists demonstrate high self-reported professional readiness for innovative oncology therapies; however, the perceived timely patient access remains constrained primarily by financial, organizational, and reimbursement-related factors. Although, these findings reflect physicians' perceptions and do not establish causal determinants of access, strengthening reimbursement pathways, HTA implementation, molecular diagnostic capacity, and clinical research infrastructure may improve equitable access to innovative oncology therapies within the evolving European HTA framework.

Indexed as

health technology assessmentinnovative oncology therapiesoncologypatient accessphysiciansprecision medicineRegulation (EU) 2021/2282reimbursement

Identifiers

PMID42793466
PMCPMC13606224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.