ReviewCurrent issues in molecular biology2026
MicroRNA-Mediated Regulation of Ionizing Radiation Responses: Mechanisms and Advances in Clinical Translation.
Review in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Ionizing radiation can induce DNA damage through direct or indirect mechanisms and activate the DNA damage response network, thereby influencing cellular repair, cell cycle regulation and cell fate determination. MicroRNAs (miRNAs), as key post-transcriptional regulatory factors, play a vital role in modulating the radiation response and cell fate. This review summarizes radiation-induced changes in miRNA expression and the molecular regulatory mechanisms they mediate, and further discusses recent advances in their application in the assessment of radiation damage, the prediction of radiotherapy response, and therapeutic interventions. Although miRNAs possess significant translational value, their multi-target regulatory characteristics, tissue- and environment-dependence, as well as limitations in clinical detection and delivery systems, continue to hinder their application. In the future, the integration of multi-omics technologies, artificial intelligence analysis and precision delivery strategies is expected to further elucidate the miRNA-mediated radiation response network and advance their application in precision radiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.