In one paragraphArticle in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
19 authors.
Chiara FossatiDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-2870-7185 Federica ArmeliDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-4981-3374 Alessandra D'AmicoDepartment of Health and Life Sciences, European University of Rome, 00163 Rome, Italy.
Giacomo FratiDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0003-2703-3761 Giovanni Enrico CasciaroDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-9464-5461 Elena CavarrettaDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0003-0221-6000 Vittoria TestaCorso di Laurea di I Livello in Infermieristica, Sapienza University of Rome Polo Pontino-Sede di Terracina, 04019 Terracina, Italy.
Alessio BorrelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-6698-7181 Luigi SciarraDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-9669-1330 Chiara LodoliDepartment of Maternal and Child Health and Urological Sciences-Policlinico Umberto I, 00161 Rome, Italy.
Marco ZagarellaFaculty of Medicine and Surgery, Sapienza University of Rome, 04100 Latina, Italy.
Beatrice Oana PaunFaculty of Medicine and Surgery, Sapienza University of Rome, 04100 Latina, Italy.
Vittorio PicchioDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0003-1591-5118 Antonio GianfeliciDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Fabio PigozziDepartment of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0001-5808-9405 Stefano CorradoDepartment of Human Sciences, Society and Health, University of Cassino and Southern Lazio, 03043 Cassino, Italy.
Fabrizio PerroniDepartment of Biomolecular Sciences, Section of Exercise and Health Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0003-2094-4351 Cristina NocellaIstituto Pasteur Italia-Fondazione Cenci Bolognetti, 00161 Roma, Italy.
Roberto CarnevaleDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-6216-9595 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
backgroundIntense physical exercise induces oxidative stress and inflammation in adult professional athletes, but data on adolescent elite athletes remain limited.
methodsTwenty-four elite adolescent soccer players were recruited and evaluated three times: pre-season baseline (T0), after one month of pre-season training (T1), and at the end of the first half of the competitive season (T2, approximately 4 months after T0). Saliva samples were collected as non-invasive surrogate indicators reflecting oxidative stress- and endothelial-related signaling. In vitro studies were performed on endothelial cells exposed to H
resultsAthletes showed a significant increase in salivary oxidative stress markers (NOX2 levels and H
conclusionsOur findings indicate that adolescent elite athletes experience significant salivary oxidative stress- and endothelial-related alterations, potentially reflecting cardiovascular stress. These results underscore the importance of cardiovascular monitoring and the potential benefits of antioxidant strategies, even in young athletes participating in high-intensity sports.
Indexed as
AthletesEndothelial CellsNADPH Oxidase 2Oxidative StressSoccerAdolescentBiomarkersEndothelin-1Endothelium, VascularHumansHydrogen PeroxideMaleNitric Oxide Synthase Type IIISalivaBiomarkersCYBB protein, humanEndothelin-1Hydrogen PeroxideNADPH Oxidase 2Nitric Oxide Synthase Type IIIadolescent elite athletesendothelial impairmentNOX2oxidative stresssalivary biomarkers
Identifiers
PMID42793133
PMCPMC13604306
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