Evidence map›Paper›PMID 42793104›Full record

ReviewBiomolecules2026

Nutriepigenetics in Skin Homeostasis: Molecular Mechanisms of Honey-Mediated Chromatin Remodeling in Non-Healing Ulcers.

Elia Ranzato, Simona Martinotti

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elia RanzatoDiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy.ORCID 0000-0002-7600-8215
Simona MartinottiDiSIT-Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy.ORCID 0000-0003-2891-1810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional wound therapies continue to be predominantly exogenous and address extracellular causes of the pathology without addressing the impaired function of cellular pathways that are trapped in the state of constant inflammation. The present review explores a novel putative nutriepigenetic framework, discussing how the honey matrix could act as a proposed modulator of the altered epigenetic landscape in non-healing ulcers. Honey contains a complex mixture of bioactive agents (polyphenols, flavonoids, and plant-derived xenomiRs) that are hypothesized to interact with multiple chromatin control points simultaneously. We discuss models wherein honey-induced aquaporin-mediated H

Indexed as

Chromatin Assembly and DisassemblyEpigenesis, GeneticHomeostasisHoneySkinAnimalsHumansWound Healingchromatin remodelingepigenetic memoryepithelial–mesenchymal transitionnutriepigeneticswound healing

Identifiers

PMID42793104
PMCPMC13604045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.