Evidence map›Paper›PMID 42793075›Full record

ArticleBiomolecules2026

Hibiscus Suspension Culture Extract Modulates Skin Metabolism and Cellular Pathways in Human Keratinocyte/Fibroblast Co-Cultures: A Proteomic Approach.

Rachid Anane, Su Melser, Elodie Renouf, Rachid Ennamany, Jean-Michel Mérillon

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachid AnaneNaolys, 86 Route d'Arcachon, 33610 Cestas-Pierroton, France.
Su MelserElysia Bioscience, 40 Avenue Ferdinand de Lesseps, 33610 Canéjan, France.
Elodie RenoufPolyphenols Biotech, Equipe Molécules d'Intérêt Biologique, UMR 1366 INRAE, Faculté des Sciences Pharmaceutiques, Université de Bordeaux, 210 Chemin de Leysotte, 33140 Villenave d'Ornon, France.
Rachid EnnamanyNaolys, 86 Route d'Arcachon, 33610 Cestas-Pierroton, France.
Jean-Michel MérillonPolyphenols Biotech, Equipe Molécules d'Intérêt Biologique, UMR 1366 INRAE, Faculté des Sciences Pharmaceutiques, Université de Bordeaux, 210 Chemin de Leysotte, 33140 Villenave d'Ornon, France.

Funding

the Bordeaux Metabolome Facility ANR- 11-INBS-0010 project
6 · The paper itself

Abstract

Hibiscus plant cell cultures were developed to produce a cosmetic ingredient with anti-ageing properties. UHPLC-DAD-MS analysis of Hibiscus plant cell cultures revealed a high content of polyphenols, particularly hydroxycinnamic acid derivatives, including caffeoyl and p-coumaroyl conjugates. The biological activity of a 50/50 mixture of extracts from

Indexed as

FibroblastsHibiscusKeratinocytesPlant ExtractsProteomicsSkinCoculture TechniquesHumansProteomePlant ExtractsProteomeHibiscus rosa sinensisHibiscus syriacuskeratinocyte/fibroblast co-culturephytochemicalsplant cell culturepolyphenolsproteomics

Identifiers

PMID42793075
PMCPMC13604347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.