Evidence map›Paper›PMID 42793063›Full record

ArticleBiomolecules2026

Structural and Functional Interrogation of Active

Eunjeong Lee, Blaine Hunter Gordon, Jasmina S Redzic, Anthony J Saviola, Sean P Maroney, Steven Shaw, Mila Cordero, Shaun Bevers, Angelo D'Alessandro, Kirk C Hansen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eunjeong LeeDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Blaine Hunter GordonDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Jasmina S RedzicDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Anthony J SaviolaDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-6890-512X
Sean P MaroneyDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Steven ShawDepartment of Otolaryngology-Head & Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Mila CorderoDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Shaun BeversDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-2000-6106
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-2258-6490
Kirk C HansenDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Sarah E ClarkDepartment of Otolaryngology-Head & Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-5975-5032
Elan EisenmesserDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-6967-0892

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Airway Prevotella enhance innate immune-mediated protection against lung infectionR01AI172958 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Sarah E Clark · 2023 to 2026
$2.0M
900 MHz NMR console and probesS10OD034299 · OD · UNIVERSITY OF COLORADO DENVER · PI JONES, DAVID NIGEL · 2023 to 2023
$1.1M
The Molecular Basis of Staphylococcus aureus SplB manipulation of the hostR01AI189606 · NIAID · UNIVERSITY OF COLORADO DENVER · PI ELAN Z EISENMESSER · 2025 to 2026
$780k
600 MHz NMR console and cold probeS10OD025020 · OD · UNIVERSITY OF COLORADO DENVER · PI JONES, DAVID NIGEL · 2018 to 2018
$501k
NCI NIH HHS P30 CA046934NIAID NIH HHS R01 AI172958NIAID NIH HHS R01 AI189606NIH HHS S10 OD025020NIH HHS S10 OD034299
6 · The paper itself

Abstract

Sortase A (SrtA) enzymes covalently anchor surface proteins to Gram-positive bacterial cell walls, promoting colonization and virulence. In

Indexed as

AminoacyltransferasesBacterial ProteinsCysteine EndopeptidasesStreptococcus pneumoniaeCatalytic DomainSubstrate SpecificityAminoacyltransferasesBacterial ProteinsCysteine Endopeptidasessortase AenzymeNMRSortase AStreptococcus pneumoniae

Identifiers

PMID42793063
PMCPMC13604702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.