Evidence map›Paper›PMID 42793009›Full record

ReviewGenes2026

A Strategic Implementation Framework for Integrating Pharmacogenomics (PGx) into Personalized Healthcare in Saudi Arabia.

Kholud R Alrubaie, Raghad A Alzaylaee, Latifah A Alayyaf, Farjah H Algahtani, Shaker A Alomary, Abdullah M Assiri, Mariam M AlEissa

Abstract readReview
In one paragraph

Review in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kholud R AlrubaiePopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.
Raghad A AlzaylaeePopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.
Latifah A AlayyafPopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.
Farjah H AlgahtaniOncology Center, Chair of Epidemiology and Public Health Research, King Saud University, Riyadh 12373, Saudi Arabia.ORCID 0000-0002-6552-6260
Shaker A AlomaryPopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.ORCID 0000-0002-4283-6725
Abdullah M AssiriPopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.
Mariam M AlEissaPopulation Health Observatory, Ministry of Health, Riyadh 11176, Saudi Arabia.ORCID 0000-0002-2355-4036

Funding

King Saud University ORF-RC-2026-25- 03
6 · The paper itself

Abstract

Pharmacogenomics has the potential to improve the safety and efficacy of medicines in Saudi Arabia, and has a strong basis for implementation through population-specific genomic evidence, growing laboratory capacity and national digital health investment. We undertook a structured policy analysis and evidence synthesis of Saudi, regional, and international evidence; compared selected implementation capabilities across established models; and assessed national readiness descriptively across key health system domains. Using published evidence and structured expert judgement, we propose gene-drug priority tiers according to their clinical impact, population relevance and feasibility. Saudi Arabia's strengths are in genomic evidence and digital health infrastructure, but large gaps exist in governance, laboratory standardization, electronic health record interoperability, clinical decision support, workforce readiness, reimbursement, and outcome evaluation. Five pathways are proposed for initial implementation:

Indexed as

PharmacogeneticsPrecision MedicineDigital HealthHumansSaudi Arabiaclinical implementationpersonalized medicinepharmacogenomicspopulation health observatoryprecision medicineSaudi ArabiaVision 2030

Identifiers

PMID42793009
PMCPMC13606155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.