Evidence map›Paper›PMID 42792906›Full record

ArticleGenes2026

Primary Ciliary Dyskinesia from Embryogenesis to Adulthood: Micro-CT Analysis of Stage-Dependent Upper Airway Abnormalities in

Tiziana Orsini, Sabrina Putti, Francesco Chiani, Alessia Gambadoro, Miriam Pasquini, Olga Ermakova

Abstract read
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tiziana OrsiniInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0003-0023-7916
Sabrina PuttiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0003-3335-043X
Francesco ChianiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0002-8887-3900
Alessia GambadoroInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0002-3563-2759
Miriam PasquiniInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0001-6500-8909
Olga ErmakovaInstitute of Biochemistry and Cell Biology (IBBC), National Research Council of Italy (CNR), Adriano Buzzati-Traverso Campus, Via Ramarini, 32, 00015 Monterotondo, Italy.ORCID 0000-0001-8365-4904

Funding

National Research Council DSB.AD009.001
6 · The paper itself

Abstract

BACKGROUND/

objectivesPrimary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by impaired ciliary function, leading to chronic airway disease. Loss-of-function mutations in

methodsConstitutive (

resultsGenetic dissection revealed a marked dependence of the phenotype on whether

conclusionsThis study characterizes the structural timeline of upper airway pathology in PCD and validates the

Indexed as

Ciliary Motility DisordersKartagener SyndromeAnimalsCiliaDisease Models, AnimalEmbryonic DevelopmentFemaleLoss of Function MutationMiceMice, KnockoutPhenotypeX-Ray MicrotomographyCcdc151ciliopathyconditional knockout mousemicro-computed tomographymouse modelsmucociliary clearanceOdad3primary ciliary dyskinesiaupper airway developmentvirtual histology

Identifiers

PMID42792906
PMCPMC13606073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.