Evidence map›Paper›PMID 42792893›Full record

ArticleGenes2026

A Novel Loss-of-Function Variant in

Shujie Hou, Siyao Li, Xinluo Wang, Shiying Zhang, Yuntao Lu, Ting Zhang, Zhibo Zhou, Wenbin Huang, Xuedong Wang, Bing Han and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shujie HouDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Siyao LiDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Xinluo WangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Shiying ZhangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Yuntao LuDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Ting ZhangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Zhibo ZhouDepartment of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.
Wenbin HuangGuangdong Provincial High-Level Clinical Key Specialty, Guangdong Province Engineering Research Center of Oral Disease Diagnosis and Treatment, Department of Orthodontics, Stomatological Center, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, China.
Xuedong WangCenter of Stomatology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing 102218, China.ORCID 0000-0002-9366-7298
Bing HanDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.ORCID 0000-0003-4584-1092
Jieni ZhangDepartment of Orthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology Beijing/National Clinical Research Center for Oral Diseases Beijing/National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing, Beijing 100081, China.

Funding

National Key Research and Development Program of China 2024YFC2510702National Natural Science Foundation of China 52473120National Natural Science Foundation of China 8237030822Peking University School and Hospital of Stomatology PKUSSNCT-24A05
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cleft LipCleft PalateExtracellular Matrix ProteinsLoss of Function MutationTransforming Growth Factor betaAnimalsbetaIG-H3 ProteinChinaEast Asian PeopleExome SequencingFemaleHumansMaleMicePedigreebetaIG-H3 ProteinExtracellular Matrix ProteinsTransforming Growth Factor betacraniofacial anomalyloss-of-function mutationnon-syndromic orofacial cleftTGFBIwhole-exome sequencing

Identifiers

PMID42792893
PMCPMC13606577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.