Urinary Volatilomic Profiling Reveals Candidate Metabolomic Signatures Associated with Colorectal Cancer.

Francisca Viveiros, Pedro H Berenguer, Isabel Jardim, Miguel Camacho, Ana Célia Sousa, Rosa Perestrelo, José S Câmara

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francisca ViveirosCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.

Pedro H BerenguerCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0001-8305-2938

Isabel JardimServiço de Gastrenterologia, Hospital Dr. Nélio Mendonça, SESARAM, EPERAM, Avenida Luís de Camões, nº57, 9004-514 Funchal, Portugal.

Miguel CamachoServiço de Gastrenterologia, Hospital Dr. Nélio Mendonça, SESARAM, EPERAM, Avenida Luís de Camões, nº57, 9004-514 Funchal, Portugal.

Ana Célia SousaCentro de Investigação Dra. Maria Isabel Mendonça, Hospital Dr. Nélio Mendonça, SESARAM, EPERAM, Avenida Luís de Camões, nº57, 9004-514 Funchal, Portugal.

Rosa PerestreloCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0002-7223-1022

José S CâmaraCQM-Centro de Química da Madeira, Campus Universitário da Penteada, Universidade da Madeira, 9020-105 Funchal, Portugal.ORCID 0000-0003-1965-3151

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, largely due to delayed diagnosis. Current screening approaches are limited by invasiveness, cost, and low patient adherence, underscoring the urgent need for non-invasive biomarkers that could complement the existing strategies. Cancer-associated metabolic reprogramming, together with alterations in host-microbiota interactions, is reflected in the urinary volatilome, offering a potential source of candidate biomarkers. In this exploratory, case-control pilot study, urinary volatile organic metabolites (VOMs) were profiled in patients with colorectal cancer (CRC,

Indexed as

biomarkerscolorectal cancerexploratory studySPME/GC-MSstatistical analysisurine

Identifiers

PMID42792524

DOI10.3390/biology15181578

PMCPMC13603885

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.