ReviewBehavioral sciences (Basel, Switzerland)2026
Effectiveness of School-Based Integrated Mental Health and Substance Use Prevention Programs for Adolescents: A Systematic Review and Meta-Analysis.
Review in Behavioral sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
School-based prevention programs increasingly incorporate mental health-related components to prevent substance use among adolescents. This study aimed to evaluate the effectiveness of integrated school-based mental health and substance use prevention programs for adolescents through a systematic review and meta-analysis. A systematic literature search was conducted across 12 electronic databases for studies published between January 2016 and April 2026. Randomized controlled trials (RCTs) and cluster randomized controlled trials evaluating school-based integrated prevention programs for adolescents were included. Random-effects meta-analyses were performed for substance-use outcomes, including alcohol-related outcomes and binge drinking, using pooled odds ratios (ORs) and 95% confidence intervals (CIs). Mental health and psychosocial outcomes were synthesized narratively because heterogeneity in outcome definitions, measurement instruments, and assessment periods precluded meaningful quantitative pooling. A total of 16 reports representing 10 independent trials were included in the systematic review, and five independent trial comparisons were included in the primary meta-analysis. Integrated prevention programs significantly reduced alcohol-related behaviors among adolescents compared to control groups (OR = 0.56, 95% CI = 0.37-0.86,
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