Evidence map›Paper›PMID 42792132›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Berberine Chloride Suppresses Growth of Canine Osteosarcoma Cells via Regulating MMP2/AKT/β-Catenin Pathway.

Minha Jeong, Juhyeong Seo, Sunwoo Park, Jiyeon Ham

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minha JeongDepartment of Animal Science & Biotechnology, College of Agriculture and Life Sciences, Chungnam National University, Daejeon 34134, Republic of Korea.
Juhyeong SeoDepartment of Animal Science & Biotechnology, College of Agriculture and Life Sciences, Chungnam National University, Daejeon 34134, Republic of Korea.
Sunwoo ParkDepartment of GreenBio Science, Gyeongsang National University, Jinju-si 52725, Republic of Korea.
Jiyeon HamDepartment of Animal Science & Biotechnology, College of Agriculture and Life Sciences, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0000-0002-3145-2726

Funding

Chungnam National University 2023-1657-01 & 2024-0882-01
6 · The paper itself

Abstract

Canine osteosarcoma is an aggressive primary bone malignancy associated with a poor prognosis and a high propensity for lung metastasis. Due to the limitations and side effects of conventional chemotherapy, there remains a pressing need for alternative therapeutic strategies and adjuvants. In this study, we examined the effects of berberine chloride (BBRC), a bioactive isoquinoline alkaloid derived from the dried roots of

Indexed as

calcium homeostasismigrationosteosarcomaROSviability

Identifiers

PMID42792132
PMCPMC13603218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.