Evidence map›Paper›PMID 42792127›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Genome-Wide Association Study Reveals Novel Loci and Candidate Genes of Vitamin E Content in Sesame (

Zishu Luo, Jianglong Zhou, Yijia Zhang, Huan Li, Rong Zhou, Ting Zhou, Yanxin Zhang, Jun You, Linhai Wang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Zishu LuoKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Jianglong ZhouKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Yijia ZhangKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Huan LiKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0002-8778-7568
Rong ZhouKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Ting ZhouKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.
Yanxin ZhangKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0001-6655-0484
Jun YouKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0001-8927-1015
Linhai WangKey Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China.ORCID 0000-0002-5537-7898

Funding

Central Public-interest Scientific Institution Basal Research Fund 1610172023003China Agriculture Research System CARS-14Hubei International Science and Technology Cooperation Project 2024EHA055National Center for Crops Germplasm Resources NCCGR-2025-016the Agricultural Science and Technology Innovation Program of Chinese Academy of Agricultural Sciences CAAS-ASTIP-2026-OCRIthe Science and Technology Innovation Project of Hubei province 2025-620-000-001-031
6 · The paper itself

Abstract

Sesame is a significant oilseed crop whose exceptional oxidative stability is closely associated with its abundant endogenous antioxidants. As one of the most predominant lipid-soluble antioxidants in sesame, vitamin E (VE) plays a critical role in scavenging lipid peroxyl radicals, terminating lipid peroxidation chain reactions, and protecting cellular membranes from oxidative damage, thereby maintaining intracellular redox homeostasis and attenuating the development of oxidative stress-related disorders. Although VE is a potent natural antioxidant with significant pharmacological activities in mitigating oxidative stress-related disorders, the genetic mechanisms underlying the natural variation in VE content in sesame remain incompletely understood. Here, variation in VE content was evaluated across 400 sesame accessions grown in two environments. Ultra-high-performance liquid chromatography (UHPLC) analysis revealed that only γ-tocopherol was detected in sesame seeds, with concentrations between 169.33 and 463.31 mg/kg, averaging 316.28 mg/kg. The newly acquired SNP and InDel data from whole-genome resequencing were associated with the phenotypic data, leading to the identification of five significant loci associated with VE content. Comparative transcriptomic profiling of two sesame accessions with distinct VE contents revealed the differential expression of key biosynthetic enzyme genes (such as

Indexed as

genome-wide association studysesametranscriptomevitamin E

Identifiers

PMID42792127
PMCPMC13603810

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