Evidence map›Paper›PMID 42792120›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Ergothioneine-Derived Carbon Dot Nanozymes Alleviate the Oxidative Stress Microenvironment to Delay Intervertebral Disc Degeneration.

Ziyang Zhang, Kehan Wang, Hao Chen, Yu Shi, Huihui Wang

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ziyang ZhangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China.
Kehan WangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China.
Hao ChenThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China.
Yu ShiThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China.
Huihui WangThe First School of Clinical Medicine, Faculty of Medicine, Yangzhou University, Yangzhou 225009, China.

Funding

National Natural Science Foundation of China 32401165
6 · The paper itself

Abstract

Nucleus pulposus cells (NPCs) age mainly because reactive oxygen species (ROS) build up too much. Excess ROS is associated with intervertebral disc degeneration (IVDD). In this study, we prepared ergothioneine-derived carbon dots (EGT-Fe-CDs) as an antioxidant nanozyme. EGT-Fe-CDs showed good biocompatibility, superoxide dismutase-like and catalase-like activities, and high total antioxidant capacity. In H

Indexed as

ergothioneine-derived carbon dotsintervertebral disc degenerationnanozymenucleus pulposus cellsoxidative stress

Identifiers

PMID42792120
PMCPMC13603896

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.