ArticleAntibiotics (Basel, Switzerland)2026
Discovery of a Novel Benzothiophene Inhibitor of Penicillin-Binding Protein 2 with Potent Gram-Positive Activity.
Monica A Stefaniak, Vijay Singh Gondil, Jingdong Yang, Adil Omar, Allen G Oliver, Ansley M Nemeth, Roberta J Melander, Mayland Chang, Paul M Dunman, Christian Melander
Abstract read
In one paragraphArticle in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Monica A StefaniakDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0009-0007-9293-1222 Vijay Singh GondilDepartment of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0001-5603-7345 Jingdong YangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0009-0008-1303-9007 Adil OmarDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Allen G OliverDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0000-0002-0511-1127 Ansley M NemethDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0000-0001-7249-5688 Roberta J MelanderDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0000-0002-3548-3351 Mayland ChangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID 0000-0002-4333-3775 Paul M DunmanDepartment of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Christian MelanderDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Funding
Project 2: Defining the Protective vs. Susceptible Immune Proteome of S. aureus OsteomyelitisP50AR072000 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2017 to 2026
$13.6MNIAMS NIH HHS P50 AR072000NIH HHS P50 AR072000
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
antibacterialbenzothiophenemethicillin-resistant Staphylococcus aureuspenicillin-binding proteins (PBPs)transglycosylase
Identifiers
PMID42791976
PMCPMC13603487
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