Evidence map›Paper›PMID 42791892›Full record

ArticleBioengineering (Basel, Switzerland)2026

Pre-Deployment Audit of Actionability and Equity in Severe Tooth Loss Prediction Using Constrained Algorithmic Recourse and Temporal Validation.

Quang Tuan Lam, Fang-Yu Fan, Tzu-Yu Peng, Sheng-Wei Feng, Cathy Chia-Yu Huang, Tong-Hsien Chow, Minh Huu Nhat Le, Giang Vu, Yung-Li Wang, Nguyen Quoc Khanh Le and 1 more

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Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Quang Tuan LamSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0009-0004-5305-2266
Fang-Yu FanSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-5176-4102
Tzu-Yu PengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-7168-9429
Sheng-Wei FengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-6637-7044
Cathy Chia-Yu HuangDepartment of Life Sciences, National Central University, Taoyuan City 32001, Taiwan.
Tong-Hsien ChowDepartment of Sports Science, R.O.C. Military Academy, Kaohsiung 83059, Taiwan.ORCID 0000-0002-7013-2979
Minh Huu Nhat LeSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06520, USA.ORCID 0000-0002-7728-1539
Giang VuSchool of Global Health Management and Informatics, University of Central Florida, Orlando, FL 32801, USA.ORCID 0000-0003-1159-6973
Yung-Li WangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-0633-8913
Nguyen Quoc Khanh LeAIBioMed Research Group, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-4896-7926
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-8451-0280

Funding

National Science and Technology Council NSTC 115-2314-B-038-057
6 · The paper itself

Abstract

backgroundPredictive performance does not establish whether model-identified risks correspond to feasible, equitable pathways. We assessed the actionability and equity of a severe tooth loss prediction model using constrained algorithmic recourse and same-source temporal validation.

methodsAn Explainable Boosting Machine was trained using 2022 Behavioral Risk Factor Surveillance System data from 433,772 adults. High-risk adults underwent recourse auditing incorporating immutability locks, behavioral directionality, physiological safety floors, and at most three feature changes. Recourse represented hypothetical movement within model space, not treatment advice, causal risk reduction, or reversal of tooth loss. Primary reachability was the unweighted analytic-cohort proportion for which the frozen engine identified a feasible pathway; a BRFSS survey-weighted domain sensitivity analysis used final weights, strata, and primary sampling units. The audit separated reachability from conditional burden among reachable adults. Equity was evaluated across Social Indicators of Disparity Index (SIDI) and income strata using Oaxaca-Blinder decomposition. The frozen specification was evaluated in a 2022 holdout and the 2024 BRFSS cohort (

resultsSurvey-weighted areas under the receiver operating characteristic curve were 0.858, 0.855, and 0.858 in the 2022 full, 2022 holdout, and 2024 cohorts. Primary unweighted reachability was 10.61%, 10.54%, and 9.82%; corresponding survey-weighted estimates were 12.69% (95% design-aware CI, 12.33-13.07%), 12.31% (11.54-13.12%), and 11.30% (10.95-11.65%), respectively. Thus, reachability remained limited under both estimands. The high-SIDI group showed poorer calibration. Under the prespecified primary SIDI-neutral additive-cost specification, residual conditional cost differences across SIDI strata were small; alternative burden metrics were direction-dependent. The income residual attenuated from the 2022 holdout to 2024, although its confidence intervals were fixed-pipeline row-bootstrap intervals rather than fully design-based intervals.

conclusionsStable predictive performance masked limited model-space actionability. Integrating explicitly labeled reachability estimands, conditional burden, equity, and temporal transport can strengthen pre-deployment evaluation. Because severe tooth loss is irreversible, recourse pathways should be interpreted as a stress test of model-implied modifiable factors rather than evidence of reversibility.

Indexed as

algorithmic recourseartificial intelligencehealth equitysevere tooth losstemporal validation

Identifiers

PMID42791892
PMCPMC13603997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.