Evidence map›Paper›PMID 42791321›Full record

ReviewInternational journal of obesity (2005)2026

Bidirectional crosstalk between obesity and the lymphatic system: a novel pathway in obesity pathogenesis and treatment.

Yitong Hao, Yutong Zhang, Jiamin Zong, Gaomin Wu, Yu Wang, Junhong Wang, Yanyan Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yitong Hao *Tianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID http://orcid.org/0009-0001-0883-3694
Yutong Zhang *Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jiamin ZongTianjin University of Traditional Chinese Medicine, Tianjin, China.
Gaomin WuTianjin University of Traditional Chinese Medicine, Tianjin, China.
Yu WangTianjin University of Traditional Chinese Medicine, Tianjin, China.
Junhong WangTianjin University of Traditional Chinese Medicine, Tianjin, China. wangjh@tjutcm.edu.cn.
Yanyan WangTianjin University of Traditional Chinese Medicine, Tianjin, China. wangyanyan@tjutcm.edu.cn.ORCID http://orcid.org/0000-0003-4859-4963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has become a global public health crisis in recent years, with its continuous rise posing significant health risks. It is associated with a range of chronic diseases, including cardiovascular disease, type 2 diabetes, and certain types of cancer. Additionally, obesity leads to poor health outcomes and reduces life expectancy. The lymphatic system, a critical part of the circulatory system, has traditionally been recognized for its primary functions in immune surveillance and maintaining tissue fluid balance. Lymphatics also play a more complex role in lipid metabolism, immune regulation, and inflammation control, which significantly influences metabolic health. Despite these insights, the specific mechanisms of interaction between lymphatic dysfunction and obesity, as well as the directionality of causality, are not yet fully understood. This review aims to systematically synthesize and evaluate existing evidence regarding the interrelationship between lymphatic dysfunction and obesity. Its goal is to provide novel perspectives for developing innovative preventative and therapeutic strategies targeting lymphatic function in obesity.

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.