Evidence map›Paper›PMID 42789693›Full record

ArticleScience advances2026

Macrophage restriction in

Yoshiki Sakai, Kavya Adiga, Matin Nawabi, Sofia Mendez-Lopez, Tsai-Ching Hsi, David Bilder

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoshiki SakaiDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-6023-8358
Kavya AdigaDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-9511-892X
Matin NawabiDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0009-0005-4871-2730
Sofia Mendez-LopezDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0009-0000-2344-0795
Tsai-Ching HsiDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0001-8812-3133
David BilderDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-1842-4966

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Polarity, growth, and morphogenesis of epitheliaR35GM130388 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI David Bilder · 2019 to 2026
$6.5M
NIGMS NIH HHS R01 GM084947NIGMS NIH HHS R35 GM130388NIH HHS P40 OD018537
6 · The paper itself

Abstract

Breaches of epithelial homeostasis trigger an inflammatory response. Not only initiation but also negative regulation of the response is critical, as autoinflammation can cause tissue damage and chronic disease. Epithelial breaches can be signaled by damage-associated molecular patterns (DAMPs), including basement membrane (BM) degradation, that attract inflammatory cells. Here, we show that the conserved glycosylphosphatidylinositol-linked thioester-containing protein Tep3 from

Indexed as

Drosophila ProteinsMacrophagesNeoplasmsProtease InhibitorsWounds and InjuriesAnimalsDrosophilaDrosophila melanogasterHumansImmunity, InnateMatrix Metalloproteinase 1ProteolysisWound HealingDrosophila ProteinsMatrix Metalloproteinase 1Protease Inhibitors

Identifiers

PMID42789693
PMCPMC13614384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.