Evidence map›Paper›PMID 42789224›Full record

ArticleMedical oncology (Northwood, London, England)2026

METTL16 promotes colorectal cancer progression and CD8

Yanyan Hu, Shengying Li, Minjing Zhu, Xuedan Lin, Chaoju Gong, Zejun Fang

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanyan HuClinical Laboratory, Sanmen People's Hospital, Sanmen, China.
Shengying LiOffice of Drug Clinical Trial Institutions, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, China.
Minjing ZhuClinical Laboratory, Sanmen People's Hospital, Sanmen, China.
Xuedan LinClinical Laboratory, Sanmen People's Hospital, Sanmen, China.
Chaoju GongCentral Laboratory, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, No. 19 Zhongshan Bei Road, Xuzhou, 221100, China. gongcj@zju.edu.cn.
Zejun FangCentral Laboratory, Sanmen People's Hospital, No. 15 Taihe Road, Hairun Street, Sanmen, 317100, China. fangzejun@zjsmyy.com.ORCID https://orcid.org/0000-0002-4454-956X

Funding

National Natural Science Foundation of China 82303594Zhejiang Medical and Health Science and Technology Plan 2024XY091Zhejiang Provincial County Level Advantageous Disciplines of Traditional Chinese Medicine Construction Plan 2023-XK-D040
6 · The paper itself

Abstract

This study aims to investigate whether Methyl-Transferase-Like Protein 16 (METTL16) promotes colorectal cancer (CRC) progression through regulating branched-chain amino acid (BCAA) transaminase 1 (BCAT1)-mediated metabolism to modulate CD8

Indexed as

Amino Acids, Branched-ChainCD8-Positive T-LymphocytesColorectal NeoplasmsMethyltransferasesTransaminasesAnimalsCell Line, TumorCell ProliferationDisease ProgressionFemaleHumansMiceRNA MethylationAmino Acids, Branched-ChainBCAT1 protein, humanMethyltransferasesTransaminasesBCAT1Branched chain amino acid metabolismCD8+T cellsColorectal cancerMETTL16

Identifiers

PMID42789224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.