ArticleThe Journal of the Egyptian Public Health Association2026
Effectiveness of a self-management educational program among people with multiple sclerosis: a pre-test post-test intervention study.
Article in The Journal of the Egyptian Public Health Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBeyond pharmacological disease-modifying therapies, evidence suggests that structured self-management interventions can optimize functional independence, reduce secondary complications, and enhance quality of life. However, data from Middle Eastern multiple sclerosis (MS) populations, especially regarding telehealth-delivered self-management programs, remain scarce. Therefore, we conducted the current study to assess the effectiveness of a telehealth self-management educational program on the quality of life (QoL) of people with MS (PwMS).
methodsA one-group pre-post interventional study was conducted among 42 PwMS attending the outpatient clinic at Alexandria Main University Hospital. Baseline and post-intervention assessments were collected using a structured questionnaire comprising: (1) socio-demographic and MS-related clinical data; (2) the Multiple Sclerosis Self-Management Scale-Revised (MSSM-R); and (3) the Multiple Sclerosis International Quality of Life questionnaire (MusiQoL). Participants received a structured telehealth educational and follow-up program targeting cognitive-behavioral strategies.
resultsThe mean MSSM-R total score increased significantly from 84.7 ± 14.4 at baseline to 90.9 ± 13.8 immediately post-intervention and 96.1 ± 14.3 at 3 months (p < 0.001). Significant improvements were observed in knowledge (13.6 ± 3.7 to 17.1 ± 2.4), health maintenance behavior (12.5 ± 3.8 to 15.7 ± 3.0), and treatment adherence (26.4 ± 7.4 to 29.2 ± 6.4) (all p < 0.001). The total MusiQoL score increased from 59.8 ± 15.2 at baseline to 65.7 ± 14.8 at 3 months (p < 0.001). Significant improvements were observed in activities of daily living (p = 0.015), psychological well-being (p = 0.001), symptoms (p < 0.001), and rejection (p = 0.028), while other domains showed no statistically significant changes.
conclusionA structured telehealth-based self-management program resulted in measurable improvements in self-management capacity and quality of life in people with MS. These findings support the integration of self-management education, particularly for newly diagnosed individuals, into standard MS care and highlight the value of involving family members to reinforce patient adaptation and disease control.
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