Evidence map›Paper›PMID 42789142›Full record

ArticleMikrochimica acta2026

Portable bioactive capsule-integrated electrochemical-colorimetric dual-mode biosensor based on Mn/Ce MOF nanozyme for rapid detection of malathion in water.

Sirui Li, Shanshan Wang, Guorui Chang, Yaoxing Yang, Hui Feng, Haoqian Xue, Li Zhang, Manlin Luo, Jing Liu, Bowen Li and 1 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sirui LiCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Shanshan WangCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Guorui ChangCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Yaoxing YangCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Hui FengCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Haoqian XueCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Li ZhangDepartment of Solid Waste Treatment Technology, Sichuan Academy of Eco-Environmental Science, Chengdu, 610023, China.
Manlin LuoCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China.
Jing LiuDepartment of Solid Waste Treatment Technology, Sichuan Academy of Eco-Environmental Science, Chengdu, 610023, China.
Bowen LiCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China. libowen19@cdut.edu.cn.
Shuxia XuCollege of Ecology and Environment, State Environmental Protection Key Laboratory of Synergetic Control and Joint Remediation for Soil & Water Pollution, Chengdu University of Technology, Chengdu, 610059, China. xushux@cdut.edu.cn.ORCID https://orcid.org/0000-0002-4235-7847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To enable rapid and reliable on-site monitoring of organophosphorus pesticides a novel portable dual-mode biosensor has been developed which integrates electrochemical and colorimetric detection into a single freeze-dried bioactive capsule. This innovative design supports instrument-free operation and provides dual-signal cross-validation. The sensor is based on a newly synthesized Mn/Ce bimetallic metal-organic framework (MOF) nanozyme with high oxidase-like activity, co-immobilized with acid phosphatase (ACP) within a mannitol- and sucrose-stabilized lyophilized capsule to ensure long-term stability and field readiness. In the presence of malathion, the pesticide selectively inhibits ACP, thereby restoring the MOF's catalytic activity and enabling the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB). The resulting signal is detected both visually and through chronoamperometry after conversion to a yellow diimine product. This approach achieves a wide linear detection range of 1-2000 nM and an exceptionally low detection limit of 0.06 nM for malathion, along with high accuracy evidenced by recoveries of 93.31%-104.03% in real water samples. This work establishes a field-deployable and user-friendly sensing platform that combines innovative material design with integrated dual-mode detection, offering a robust and practical strategy for on-site environmental monitoring.

Indexed as

Biosensing TechniquesColorimetryElectrochemical TechniquesMalathionMetal-Organic FrameworksWater Pollutants, ChemicalCapsulesLimit of DetectionManganeseCapsulesMalathionManganeseMetal-Organic FrameworksWater Pollutants, ChemicalDual-mode biosensorFreeze-dried bioactive capsuleMn/Ce MOF nanozymeOn-site detectionOrganophosphorus pesticidesSignal cross-validation

Identifiers

PMID42789142

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.