Evidence map›Paper›PMID 42788636›Full record

ArticleJournal of evaluation in clinical practice2026

Duagnosis: Locating Clinical Uncertainty in the Diagnostic Framework.

Kosei Hanaoka, Daisuke Miyamori, Keiko Ogawa-Ochiai

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Article in Journal of evaluation in clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Kosei HanaokaGeneral Medicine Co-Creation Center, Kanazawa University Hospital, Kanazawa, Japan.ORCID 0009-0000-7033-2180
Daisuke MiyamoriDepartment of General Internal Medicine, Hiroshima University Hospital, Hiroshima, Japan.ORCID 0000-0002-1352-3738
Keiko Ogawa-OchiaiKampo Clinical Center, Hiroshima University Hospital, Hiroshima, Japan.ORCID 0000-0002-3277-0646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RATIONALE, AIMS AND

objectivesClinical reasoning research has predominantly operated within a single epistemological system. The prevailing response to clinical uncertainty in primary care has been to cultivate tolerance, embrace ambiguity, or learn to navigate it: each treats uncertainty as inherent to the encounter. We propose a complementary move. Much of what is called clinical uncertainty may be attributed less to the patient's condition than to the reach of the diagnostic framework through which the clinician reasons. We introduce the concept of duagnosis (dual + gnosis, 'knowing'): the clinical cognition in which two independent diagnostic systems are simultaneously activated within a single clinician's reasoning.

methodsConceptual analysis proceeding through concept definition, differentiation from neighbouring frameworks, development of the epistemological argument, and institutional comparison across East Asia. The analysis draws on clinical reasoning research, the philosophy of medicine, evidence on the care of persistent physical symptoms, and comparative scholarship on traditional medicine.

resultsThe core contribution is epistemological: what one framework cannot formulate may resolve into a recognisable, actionable pattern in another, so that uncertainty is partly a property of the framework and not only of the patient. Duagnosis can be stated in two versions: a broad sense continuous with family medicine's plural readings of the patient, and a strict sense in which the criteria of evidence themselves change. An East Asian institutional comparison shows that Japan's unified medical licence locates diagnostic duality within individual clinician cognition for every physician, a capacity medical education has not cultivated.

conclusionExpanding the diagnostic repertoire, not merely tolerating uncertainty, can reduce the proportion of presentations for which no clinical formulation exists. Locating uncertainty partly in the reach of the framework, rather than in the patient, is a reframing that applies beyond any one health system, with implications for communication and referral.

Indexed as

Clinical ReasoningPrimary Health CareAsia, EasternHumansKnowledgePhilosophy, MedicalUncertaintyclinical decision‐makingclinical reasoningepistemologymedical pluralismmedicine, Kampomedicine, traditionaluncertainty

Identifiers

PMID42788636
PMCPMC13613999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.