Evidence map›Paper›PMID 42788591›Full record

ArticleArquivos brasileiros de cardiologia2026

Incorporating Intracoronary Lithotripsy into Daily Practice: A Temporal Comparative Analysis of Safety, Efficacy, and Learning Curve.

Guy F A Prado, Stefano Garzon, José Mariani Junior, Willterson Bandeira, Felipe Mateus Teixeira Bezerra, Breno Oliveira Almeida, Gustavo Neves de Araujo, Ana Claudia Conrado, João Silveira, Emanuele Barbato and 2 more

Abstract readComparative Study
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guy F A PradoHospital Israelita Albert Einstein, São Paulo, SP - Brasil.ORCID http://orcid.org/0000-0002-6942-355X
Stefano GarzonHospital Israelita Albert Einstein, São Paulo, SP - Brasil.
José Mariani JuniorHospital Israelita Albert Einstein, São Paulo, SP - Brasil.ORCID http://orcid.org/0000-0002-0332-7530
Willterson BandeiraHospital Israelita Albert Einstein, São Paulo, SP - Brasil.
Felipe Mateus Teixeira BezerraHospital Israelita Albert Einstein, São Paulo, SP - Brasil.ORCID http://orcid.org/0009-0006-9390-7390
Breno Oliveira Almeida
Gustavo Neves de AraujoUnimed Grande Florianópolis, Florianópolis, SC - Brasil.
Ana Claudia ConradoHospital Israelita Albert Einstein, São Paulo, SP - Brasil.
João SilveiraCentro Hospitalar Universitario do Porto EPE, Porto - Portugal.
Emanuele BarbatoUniversity of Rome La Sapienza - Department of Clinical and Molecular Medicine, Rome - Itália.ORCID http://orcid.org/0000-0002-0050-5178
Flavio RibichiniUniversita degli Studi di Verona Scuola di Medicina e Chirurgia - Cardiology, Verona - Itália.ORCID http://orcid.org/0000-0002-6662-0304
Pedro Alves LemosHospital Israelita Albert Einstein, São Paulo, SP - Brasil.ORCID http://orcid.org/0000-0002-6782-750X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntravascular lithotripsy (IVL) has emerged as a groundbreaking technology for treating calcified coronary lesions.

objectiveTo assess whether case selection and interventional performance with IVL have evolved over time after its incorporation into daily practice.

methodsWe prospectively included 104 consecutive patients with 127 calcified coronary lesions treated with IVL. The cohort was divided into two temporal groups (52 patients each) based on the order of patient inclusion. Clinical data and procedural performance were compared between the groups. All statistical tests were two-sided, with a significance level of 0.05.

resultsThe mean age was 73.2 ± 10.2 years, and 62.5% of patients presented with acute coronary syndromes. Severe calcification and type B2/C lesions were identified in 73.2% and 98.4%, respectively. Upfront IVL was performed in 92.9% of lesions, intravascular imaging was used in 78%, rotational atherectomy in 6.3%, and angiographic success was achieved in 96.0%. Compared with the first cohort, the latter cohort had more bifurcation lesions (60.0% vs. 41.9%; p = 0.04), more interventions in the circumflex artery (24.6% vs. 8.1%; p = 0.02), and a lower use of 4.0-mm diameter balloons (4.6% vs. 18.5%; p = 0.02). The latter cohort spanned a longer inclusion period (168 ± 90.8 vs. 120 ± 72.8 days; p = 0.004) and had fewer angiographic complications (1.5% vs. 14.5%; p = 0.01), whereas in-hospital major adverse cardiac events did not differ (3.8% vs. 5.8%; p = 1.0).

conclusionIVL is an effective modality for coronary calcium modification. Temporal changes in case selection and interventional performance may reflect a learning-adaptation curve.

Indexed as

Coronary Artery DiseaseLearning CurveLithotripsyVascular CalcificationAgedAged, 80 and overCoronary AngiographyFemaleHumansMaleMiddle AgedPatient SelectionProspective StudiesTime FactorsTreatment Outcome

Identifiers

PMID42788591
PMCPMC13671136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.