Evidence map›Paper›PMID 42788214›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Unlocking Li/Mg-Based Photochemical Nitration Platforms for Anticancer Drug Discovery.

Qian Wan, Jiali Zhu, Shanshuo Liu, Luchuan Ou, Huizhen Wang, Yu Lan, Zhou Dong, Yihang Bai, Wei Yang, Shihan Liu and 4 more

Abstract read
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Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qian Wan *College of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Jiali Zhu *College of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Shanshuo Liu *Department of Infectious Diseases, State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Luchuan OuCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Huizhen WangDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yu LanCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.ORCID https://orcid.org/0000-0002-2328-0020
Zhou DongCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yihang BaiCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Wei YangCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Shihan LiuCollege of Chemistry and Molecular Sciences, Henan University, Kaifeng, Henan, People's Republic of China.ORCID https://orcid.org/0000-0002-5886-0260
Yan QiaoDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.ORCID https://orcid.org/0000-0001-6357-8203
Shi-Jun LiCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Zhigang RenDepartment of Infectious Diseases, State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.ORCID https://orcid.org/0000-0003-0798-3444
Linbin NiuCollege of Chemistry, State Key Laboratory of Antiviral Drugs and Pingyuan Laboratory, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.

Funding

Henan Provincial Joint Fund for Science and Technology Research and Development 222301420006Henan Provincial Joint Fund for Science and Technology Research and Development 242301420053National Natural Science Foundation of China 22101265National Natural Science Foundation of China 22531008National Natural Science Foundation of China 22571284Open Cooperation Foundation of the Department of Chemical Science of Henan University DCSHENU2401Postdoctoral Fellowship Program of CPSF GZC20250669The Changjiang (Yangtze River) Scholar Programme of the Ministry of Education of ChinaThe Ministry of Science and Technology of the People's Republic of China
6 · The paper itself

Abstract

The low toxicity and cost-effectiveness of light main-group metal photochemical systems render them highly suitable for drug development, while the redox inertness of light main-group metals significantly hinders this goal. Herein, through the in situ assembly of readily available lithium nitrate, methoxyacetic acid, and aniline substrates, an unprecedented, mild lithium-based photochemical system capable of producing valuable nitro radicals is established. This system enables selective C(sp

Indexed as

anticancer drugsLi/Mg‐based photochemistrynitrationnitro radicals

Identifiers

PMID42788214
PMCPMC13613189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.