ArticleRSC advances2026
Continuous local minocycline delivery from PLA nanosphere-coated dental implants with long-term antibacterial activity and biocompatibility.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peri-implant infections remain a major cause of dental implant failure and are often associated with bacterial colonization and biofilm formation on implant surfaces. This study aimed to develop and evaluate minocycline (MC)-coated dental implants for local antibiotic delivery and infection prevention. Drug-free poly(d,l-lactic acid) (PLA) nanospheres and free MC were co-deposited onto the implant surface. The coated implants were evaluated for drug release, antibacterial activity, biocompatibility, and osseointegration.
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Registered trials
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