Impact of residual tricuspid regurgitation after transcatheter tricuspid therapies on right and left ventricular mechanics: insights from a case series.

Giulio M Mondellini, Antoon J M van den Enden, Mark M P van den Dorpel, Christiaan L Meuwese, Nicolas M Van Mieghem

Abstract readCase Reports

In one paragraph

Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Giulio M MondelliniDepartment of Cardiology, Erasmus University Medical Center (Erasmus MC), Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-4491-4678

Antoon J M van den EndenDepartment of Cardiology, Erasmus University Medical Center (Erasmus MC), Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

Mark M P van den DorpelDepartment of Cardiology, Erasmus University Medical Center (Erasmus MC), Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

Christiaan L MeuweseDepartment of Cardiology, Erasmus University Medical Center (Erasmus MC), Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

Nicolas M Van MieghemDepartment of Cardiology, Erasmus University Medical Center (Erasmus MC), Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-2732-1205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe tricuspid regurgitation (TR) induces right ventricular (RV) volume overload and disrupts biventricular mechanics. Tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) are effective strategies to reduce or eliminate TR, yet their immediate physiological effects and the impact of residual TR remain incompletely characterized. We used invasive pressure-volume (PV) analysis to assess acute biventricular responses to transcatheter tricuspid valve interventions. Case summary: Three patients with severe TR underwent TTVR ( Discussion: Effective TR reduction appears to be a key determinant of acute biventricular adaptation following transcatheter tricuspid valve interventions. Optimal reduction (<moderate TR) is associated with RV volume unloading, increased afterload, and a coupled rise in contractile indices, resulting in improved LV filling. In contrast, suboptimal TR reduction yields limited biventricular benefit.

Indexed as

Case seriesEdge-to-edge repairHaemodynamicsPressure-volume loopRV functionTranscatheter interventionsValve replacement

Identifiers

PMID42788053

DOI10.1093/ehjcr/ytag626

PMCPMC13604847

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.