Evidence map›Paper›PMID 42787997›Full record

ArticleCureus2026

Beyond Wellens' Syndrome: Two Cases of Dynamic Electrocardiographic (ECG) Changes in Critical Left Anterior Descending Coronary Artery (LAD) Occlusion.

Nikolay N Nikolov, Rozen K Grigorov, Stefan N Yambolov, Yanko G Yankov

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikolay N NikolovDepartment of Medicine, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR.
Rozen K GrigorovDepartment of Interventional Cardiology, University Multi-profile Hospital for Active Treatment "St. Marina", Varna, BGR.
Stefan N YambolovDepartment of Interventional Cardiology, University Multi-profile Hospital for Active Treatment "St. Marina", Varna, BGR.
Yanko G YankovDepartment of Maxillofacial Surgery, University Multi-profile Hospital for Active Treatment "St. Marina", Varna, BGR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wellens' syndrome represents a high-risk electrocardiographic (ECG) manifestation of critical left anterior descending coronary artery (LAD) disease, characterized by dynamic T-wave changes that may evolve over time and precede extensive anterior myocardial infarction. In this report, we describe two patients with critical LAD disease who presented with dynamic ECG changes consistent with different Wellens' syndrome patterns, highlighting the variability of this condition. The first was a 68-year-old male patient who presented with chest pain and dyspnea. His initial ECG showed transient ST-segment elevation in the anterior leads, which later evolved into biphasic T waves, consistent with a Wellens' type A pattern. The second patient, a 62-year-old man, presented with acute chest pain and diaphoresis. Early ECG changes included transient ST-segment elevation, followed by the development of deep T-wave inversions in the precordial leads, consistent with a Wellens' type B pattern. In both cases, cardiac biomarkers were elevated, while ECG findings were either subtle or non-diagnostic in the early phase. Coronary angiography confirmed critical LAD involvement, and both patients underwent successful percutaneous coronary intervention.

Indexed as

acute coronary syndromecoronary angiographyelectrocardiographic patternleft anterior descending arterymyocardial ischemiapercutaneus coronary interventionwellens’ syndrome

Identifiers

PMID42787997
PMCPMC13602828

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.