ArticleAmerican journal of ophthalmology case reports2026
Peripheral inner retinal dimples observed on ultrawide field optical coherence tomography angiography in X-linked retinoschisis.
Article in American journal of ophthalmology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To report a novel observation of peripheral inner retinal dimples (IRDs) in a patient with X-linked retinoschisis (XLRS). Methods: A 30-year-old male with molecularly confirmed XLRS presented for his regular follow up with a new complaint of photopsia for the past month preceding examination. He underwent complete ophthalmological examination and multimodal imaging with special emphasis on peripheral retinal changes. Ultrawide-field color fundus photography, fundus autofluorescence (FAF), fluorescein angiography optical coherence tomography angiography (UWF-OCTA) were done. Results: His best corrected visual acuity (BCVA) was 20/40 in the right eye and 20/60 in the left eye with unremarkable anterior segment examination. Fundus examination demonstrated foveoschisis associated with peripheral retinal changes most notable in the inferiorotemporal quadrant manifesting as with horizontal, band-like vitreous membrane. UWF multimodal imaging confirmed presence of inner retinal dimples which corresponded to hyporeflective dark spots observed on enface OCT and UWF OCTA. Conclusion: To the best of our knowledge, this is the first report of IRDs in the inferotemporal quadrants of the peripheral retinae in a patient with XLRS.
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