ArticleIndian journal of endocrinology and metabolism
Impact of a Short-term Yoga Lifestyle Programme on Circulating Serum Klotho Levels in Patients with Type 2 Diabetes: An Exploratory Study.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Klotho, an anti-ageing protein involved in metabolic regulation, is downregulated in type 2 diabetes mellitus (T2DM). Prior studies suggest that enhancing Klotho expression may help manage diabetes and its complications. Yoga, with its systemic effects, may offer a promising non-pharmacological approach. The present study aimed to evaluate the effect of a 15-day structured yoga lifestyle (SYL) programme on serum Klotho levels and glycaemic parameters in individuals with T2DM. Methods: This single-arm, open-label exploratory study was conducted on 74 adults (30-65 years) with T2DM. The SYL programme included asanas, pranayama, meditation, kriyas, a satvik diet, and spiritual sessions. Pre- and post-assessments included serum Klotho, fasting blood glucose (FBG), postprandial blood glucose (PPBG), and blood pressure (BP). The Wilcoxon signed-rank test was used. Results: Serum Klotho levels increased significantly by 14.65% ( Conclusion: The findings support SYL as a potential adjunct therapy. Longer controlled trials are needed to further establish these results.
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