Evidence map›Paper›PMID 42787837›Full record

ArticleiScience2026

Protective

Daniel A Veronese-Paniagua, Cameron Banks, Kameron Bradley, Noyonika Mukherjee, Sarah E Gale, Kate E Hinshaw, Amy M Meacham, Opeoluwa F Iwaloye, Hubert M Tse, Clayton E Mathews and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Daniel A Veronese-PaniaguaRoy and Diana Vagelos Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63112, USA.
Cameron BanksDivision of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, MO 63112, USA.
Kameron BradleyDivision of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, MO 63112, USA.
Noyonika MukherjeeDivision of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, MO 63112, USA.
Sarah E GaleDivision of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, MO 63112, USA.
Kate E HinshawDepartment of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Amy M MeachamDepartment of Infectious Disease and Immunology, University of Florida, Gainesville, FL, USA.
Opeoluwa F IwaloyeDepartment of Infectious Disease and Immunology, University of Florida, Gainesville, FL, USA.
Hubert M TseDepartment of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Clayton E MathewsDepartment of Infectious Disease and Immunology, University of Florida, Gainesville, FL, USA.
Jeffrey R MillmanRoy and Diana Vagelos Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63112, USA.

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Determining the mechanism of IFIH1 disease-associated variants on beta-cell and immune responses in Type 1 diabetesR01DK127497 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MATHEWS, CLAYTON E, MILLMAN, JEFFREY ROBERT · 2020 to 2023
$4.7M
STUDYING THE ROLE OF THE MICROENVIRONMENT ON DIFFERENTIATION AND MATURATION OF BETA CELLSR01DK114233 · NIDDK · WASHINGTON UNIVERSITY · PI Jeffrey Robert Millman · 2017 to 2026
$3.6M
Beta-cell responses to oxidative stress and Type 1 diabetesR01DK126456 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HUNTER, CHAD S, TSE, HUBERT M · 2021 to 2025
$2.3M
Uncovering the Interplay Among Pancreatic Tissue Types, Inflammation, and Genotypes in Type 1 DiabetesR01DK138469 · NIDDK · WASHINGTON UNIVERSITY · PI Jeffrey Robert Millman, HUBERT M TSE · 2024 to 2026
$811k
NIAID NIH HHS P01 AI042288NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK114233NIDDK NIH HHS R01 DK126456NIDDK NIH HHS R01 DK127497NIDDK NIH HHS R01 DK138469
6 · The paper itself

Abstract

Genome-wide association studies have identified

Indexed as

coxsackievirus B infectionIFIH1islet stress responsesMDA5single-cell RNA sequencingstem cell-derived isletstype I interferon signaling

Identifiers

PMID42787837
PMCPMC13602225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.