Evidence map›Paper›PMID 42787824›Full record

ArticleNeurosurgery practice2026

The Incidence of Radiographic Markers of Idiopathic Intracranial Hypertension in Those With Spontaneous Cerebrospinal Fluid Leak.

Chibueze I Agwu, Jay Patel, Jesse Huang, Christopher Roxbury, Paramita Das

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Article in Neurosurgery practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chibueze I AgwuPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-2458-1025
Jay PatelPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.
Jesse HuangDepartment of Neurological Surgery, University of Chicago Medicine & Biological Sciences, Chicago, Illinois, USA.
Christopher RoxburyDepartment of Otolaryngology, Cleveland Clinic, Cleveland, Ohio, USA.
Paramita DasDepartment of Neurological Surgery, University of Chicago Medicine & Biological Sciences, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesIncreased intracranial pressure as seen in idiopathic intracranial hypertension (IIH) can lead to spontaneous cerebrospinal fluid (CSF) leaks. However, CSF leak may relieve classic signs of increased intracranial pressure, leading to a missed diagnosis of IIH. The presence of radiographic markers of IIH may be one method to predict the diagnosis without high lumbar puncture pressures. We evaluate the incidence of radiographic markers classically associated with IIH in those with spontaneous CSF leaks.

methodsA review of the electronic medical record was conducted for patients admitted for spontaneous CSF leak between January 2012 and December 2022. Demographic, radiological (optic nerve sheath diameter, presence and degree of empty sella turcica, Meckel cave size and volume), and clinical (ophthalmic examination findings, presenting symptoms, IIH diagnostic status) data were collected.

resultsThirty patients (mean age: 51.7 years) were included in the analysis. Of 14 patients with recorded preoperative or intraoperative LP pressures, 5 met the criteria for diagnosis of IIH based on elevated lumbar puncture pressure (>25 cm H

conclusionThis study provides us an incidence of IIH associated radiographic markers in the CSF leak population. Further study is needed to investigate if radiographic parameters in these patients may assist in diagnostic criteria of IIH given that papilledema and elevated lumbar pressures may not be present.

Indexed as

Idiopathic intracranial hypertensionLumbar pressureRadiographicSpontaneous cerebrospinal fluid leak

Identifiers

PMID42787824
PMCPMC13606020

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