ArticleIranian journal of basic medical sciences2026
Radiosensitization effects of BaTiO₃ and gold nanoparticles in proton therapy of pancreatic tumors: A Monte Carlo study.
Article in Iranian journal of basic medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: This study investigates the potential of barium titanate (BaTiO Materials and Methods: Using the MCNP6.1 Monte Carlo code, we modeled a 3cm pancreatic tumor in the head of the pancreas loaded with clusters of BaTiO Results: The gold nanoparticles present DEF of 1.21 and BaTiO Conclusion: Both gold and BaTiO₃ nanoparticles enhanced proton dose deposition, with gold nanoparticles producing greater macroscopic and microscopic DEFs. The results also show that microscopic dose enhancement exceeds macroscopic dose enhancement, confirming that most proton-induced dose enhancement occurs in the close vicinity of nanoparticles. Because this study is based on Monte Carlo simulations with a uniform nanoparticle distribution and without biological modeling, further experimental studies are needed to validate these findings.
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