ArticleFrontiers in veterinary science2026
A conserved virulence backbone and heterogeneous type III secretion effector profiles in historical canine otitis-associated
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Canine otitis externa provides a chronic, inflamed and frequently antimicrobial-exposed niche in which Methods: We characterized the virulence-associated genomic architecture of a historical Hungarian collection obtained from canine otitis cases in 2010 and 2017. Of the 70 isolate identifiers in the nominal range 70-139, 60 had corresponding long-read assemblies and linked VFDB screening records. One assembly was excluded after genome-based taxonomic validation showed that it did not meet the species-level criterion for Results: Primary absence-sensitive analyses were restricted to 52 genome-confirmed Conclusion: These data define a conserved historical virulence-associated genomic backbone punctuated by isolate-level effector and surface-structure variation. The detected genes are interpreted as genomic homologues and repertoire features rather than as evidence of their expression or functional contribution to pathogenicity.
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