Evidence map›Paper›PMID 42787551›Full record

ArticleiMeta2026

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent

Carey Lim, Jialing Zheng, Guoxiang Cheam, Melvin Yong, Hanrong Chen, Andrew Ting, Yahua Chen, Qingqing Wang, Niranjan Nagarajan, Yunn-Hwen Gan

Abstract read
In one paragraph

Article in iMeta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carey LimInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.
Jialing ZhengInstitute of Immunology Zhejiang University School of Medicine, Hangzhou, and Liangzhu Laboratory Hangzhou China.
Guoxiang CheamInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.
Melvin YongInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.
Hanrong ChenGenome Institute of Singapore (GIS), Agency for Science Technology and Research (A*STAR) Singapore Republic of Singapore.
Andrew TingGenome Institute of Singapore (GIS), Agency for Science Technology and Research (A*STAR) Singapore Republic of Singapore.
Yahua ChenInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.
Qingqing WangInstitute of Immunology Zhejiang University School of Medicine, Hangzhou, and Liangzhu Laboratory Hangzhou China.
Niranjan NagarajanInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.
Yunn-Hwen GanInfectious Diseases Translational Research Programme, Yong Loo Lin School of Medicine National University of Singapore Singapore Republic of Singapore.ORCID https://orcid.org/0000-0001-9881-6881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota acts as a barrier against pathogen colonization, yet how specific ecological perturbations shape the evolutionary fate of invading pathogens remains unclear. Here, we show that the mode of gut perturbation and type of dysbiosis determine whether hypervirulent

Indexed as

antibioticcapsulecolonizationgut microbiomehypermucoviscosityKlebsiella pneumoniaeshort‐chain fatty acids

Identifiers

PMID42787551
PMCPMC13601767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.