Evidence map›Paper›PMID 42787520›Full record

ReviewThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026

The Role of Extracellular Vesicles in Epstein-Barr Virus Immunology and Pathogenesis for Possible Diagnostic and Therapeutic Direction.

Raha Safari Roudsari, Nazanin Bayat, Mehdi Shabani, Razieh Dowran

Abstract readReview
In one paragraph

Review in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raha Safari RoudsariDepartment of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-9421-4127
Nazanin BayatDepartment of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran, modares.ac.ir.ORCID https://orcid.org/0009-0000-9982-5616
Mehdi ShabaniDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0003-3469-0727
Razieh DowranDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran, tums.ac.ir.ORCID https://orcid.org/0000-0002-2318-4397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV), a member of the herpesvirus family, is extremely prevalent worldwide. EBV is a double-stranded DNA virus associated with various malignancies, autoimmune diseases, and lymphomas. Transmission occurs through different means, including saliva and organ transplantation. EBV can produce and secrete vesicles that are critical in intracellular communication and valuable biomarkers in body fluids to diagnose potential diseases. They can also be utilized in targeted therapy. Exosomes are extracellular vesicles (EVs) that play a significant role in several biological processes. Some important components in EBV-related EVs can be valuable biomarkers, including proteins such as latent membrane protein 1 (LMP1) and LMP2A, microRNAs (miRNAs), and long noncoding RNAs (lncRNAs). This review explores the diagnostic and therapeutic potential of EBV-derived exosomes. It also highlights their challenges due to the lack of standardization and difficulties in exosome isolation and improving exosome-based therapy efficiencies.

Identifiers

PMID42787520
PMCPMC13602174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.