ArticleFrontiers in pediatrics2026
Association of epidural block analgesia combined with Low-dose oxytocin with pain intensity and delivery outcomes in primiparous women.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Epidural block is an effective labor analgesia method; adjunctive low-dose oxytocin may further influence uterine dynamics and clinical outcomes, but evidence in primiparas is limited. Objective: To evaluate the association of epidural analgesia combined with low-dose oxytocin with pain intensity, labor duration, delivery mode, and immediate maternal-neonatal outcomes in primiparous women. Methods: In this retrospective study, 120 eligible primiparous women who delivered between January 2023 and January 2025 were classified by analgesia regimen into a combination group (epidural analgesia plus low-dose oxytocin) or a control group (epidural analgesia alone). We compared maternal demographics, VAS pain scores, durations of each labor stage, delivery mode, postpartum blood loss, maternal adverse events, and short-term neonatal outcomes (Apgar scores, NICU admission). Results: The combination group showed markedly lower VAS scores at 30 min after analgesia, in active labor, and 2 h postpartum (3.1 ± 0.9 vs. 7.0 ± 1.0; 3.5 ± 1.0 vs. 6.8 ± 1.1; 2.8 ± 0.8 vs. 6.5 ± 1.0; all Conclusions: Epidural analgesia combined with low-dose oxytocin was associated with lower labor pain scores, shorter labor duration, and a higher rate of vaginal delivery in primiparous women, without a detectable increase in common short-term maternal or neonatal adverse events.
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